Further documentation is available here. Effectiveness is similar to mach3 plasma manual pdf antidepressants. Sertraline is taken by mouth.
In the United States the whole sale cost is about 1. 50 USD per month as of 2018. In 2013 there were over 41 million prescriptions, making it the most prescribed antidepressant and second most prescribed psychiatric medication in the United States. Evidence does not show a benefit in children with depression. The comparative efficacy of sertraline and TCAs for melancholic depression has not been studied. A 1998 review suggested that, due to its pharmacology, sertraline may be more efficacious than other SSRIs and equal to TCAs for the treatment of melancholic depression. Sertraline had much lower rates of adverse effects than these TCAs, with the exception of nausea, which occurred more frequently with sertraline.
In addition, sertraline appeared to be more effective than fluoxetine or nortriptyline in the older-than-70 subgroup. A 2003 trial of sertraline vs. With respect to safety duloxetine and venlafaxine increased worsened dizziness, however not much safety data was reported. Sertraline is effective for the treatment of OCD in adults and children.